BEYOND TOMATOES: LYCOPENE AS AN ADJUNCT IN PERIODONTAL INFLAMMATION CONTROL
DOI:
https://doi.org/10.56238/revgeov17n5-039Keywords:
Lycopene, Periodontitis, Oxidative Stress, Antioxidants, Inflammation, Adjunctive Therapy, Periodontal TreatmentAbstract
Objective: To evaluate the role of lycopene as an adjunctive agent in periodontal therapy, focusing on its antioxidant and anti-inflammatory effects on periodontal parameters.
Methods: A narrative review of experimental and clinical studies investigating lycopene supplementation in patients with periodontitis was conducted.
Results: Available evidence suggests that lycopene exhibits significant antioxidant properties capable of reducing oxidative stress associated with periodontal disease. Clinical studies indicate improvements in key periodontal parameters, including reductions in gingival inflammation, BOP, and PD, when lycopene is used as an adjunct to conventional periodontal therapy. Additionally, modulation of inflammatory mediators and decreased levels of reactive oxygen species were observed, supporting its biological plausibility.
Conclusion: Lycopene shows potential as a beneficial adjunct in periodontal therapy by targeting oxidative stress and inflammation. Although current findings are promising, the heterogeneity of study designs and limited number of high-quality randomized clinical trials warrant further research to establish standardized protocols and confirm long-term clinical benefits.
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