EVALUACIÓN DE MICROPLÁSTICOS EN HÍGADO, RIÑÓN, CEREBRO Y MÚSCULO DEL PEZ CYPHOCHARAX VOGA

Autores/as

  • Daniela Correia de Silveira
  • Kelly Correia de Lima
  • Uwe Horst Schulz
  • Amanda Gonçalves Kieling
  • Marcelo Oliveira Caetano
  • Luciana Paulo Gomes

DOI:

https://doi.org/10.56238/revgeov17n5-005

Palabras clave:

Microplásticos, Cyphocharax voga, Nile Red, Bioacumulación, Contaminación de Agua Dulce

Resumen

La contaminación por microplásticos (MPs) representa una amenaza emergente para la salud de los ecosistemas acuáticos. Este estudio investigó las concentraciones de MPs en los tejidos de hígado, cerebro, riñón y músculo de individuos de la especie Cyphocharax voga recolectados en el Río dos Sinos, un recurso hídrico ubicado en una región urbanizada del sur de Brasil. Utilizando la tinción con Nile Red y microscopía de fluorescencia, se determinaron las concentraciones de MPs por gramo de tejido y se identificaron según su forma y tamaño. La mayor concentración media de MPs por gramo se observó en el tejido cerebral (192 ± 124 MP/g), seguida por el hígado (65 ± 37 MP/g), el riñón (47 ± 25 MP/g) y el tejido muscular (39 ± 24 MP/g). El análisis reveló diferencias significativas en la concentración de MPs entre los sexos de los peces en los tejidos hepático y cerebral. También se observó una correlación estadísticamente significativa entre riñón e hígado (r = -0,520; p = 0,019), así como entre riñón y cerebro (r = -0,424; p = 0,039). En cuanto a la morfología de los MPs, los fragmentos fueron la forma predominante en todos los órganos y en el tejido muscular, presentando diferencias significativas en comparación con las demás formas (espumas/films, esferas y fibras). Estos resultados demuestran la presencia de MPs en todos los tejidos analizados y destacan el cerebro como un órgano sensible para estudios de biomonitoreo. Este trabajo aporta información relevante sobre la ocurrencia de MPs en peces de agua dulce y puede contribuir a futuros estudios sobre los riesgos que estos contaminantes representan para los ambientes acuáticos, ya que estos organismos pueden servir como modelos para otros vertebrados y potencialmente para los seres humanos.

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Referencias

Adeogun, A.O., Ibor, O.R., Omiwole, R., Chukwuka, A.V., Kumuyi, O., Arukwe, A., 2020. Sex-differences in physiological and oxidative stress responses and heavy metals burden in the black jaw tilapia, Sarotherodon melanotheron, from a tropical freshwater dam (Nigeria). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 229, 108676. https://doi.org/10.1016/j.cbpc.2019.108676.

Ahmadi, A., Moore, F., Keshavarzi, B., Soltani, N., Sorooshian, A., 2022. Potentially toxic elements and microplastics in muscle tissues of different marine species from the Persian Gulf: Levels, associated risks, and trophic transfer. Marine Pollution Bulletin, 175, 113-283. https://doi.org/10.1016/j.marpolbul.2021.113283.

Alexander, J., Barregård, L., Bignami, M., Ceccatelli, S., Cottrill, B., Dinovi, M., Edler, L., Grasl-Kraupp, B., Hogstrand, C., Hoogenboom, L., Knutsen, H.K., Nebbia C.S., Oswald, I., Petersen, A., Rogiers, V.M., Rose, M., Roudot, A-C., Schwerdtle, T., Vleminckx, C., Vollmer, G., Wallace, H., 2016. Presence of microplastics and nanoplastics in food, with particular focus on seafood. EFSA Journal, 14, issue 6. https://doi.org/10.2903/j.efsa.2016.4501.

Al-Yousuf, M.H., El-Shahawi, M.S., Al-Ghais, S.M. 2000.Trace metals in liver, skin and muscle of Lethrinus lentjan fish species in relation to body length and sex. Science of The Total Environment, v. 256, n. 2–3, p. 87–94. https://doi.org/10.1016/S0048-9697(99)00363-0.

Atamanalp, M., Köktürk, M., Uçur, A., Duyar, H.A., Özdemir, S., Parlak, V., Esenbuğa, N., Alak, G., 2021. Microplastics in tissues (brain, gill, muscle and gastrointestinal) of Mullus barbatus and Alosa immaculata. Archives of Environmental Contamination and Toxicology, 81, 460–469. https://doi.org/10.1007/s00244-021-00885-5.

Avio, C.G., Gorbi, S., Regoli, F. 2015. Experimental development of a new protocol for extraction and characterization of microplastics in fish tissues: first observations in commercial species from Adriatic Sea. Marine Environmental Research, v. 112, p. 18-28. https://doi.org/10.1016/j.marenvres.2015.06.014.

Barboza, L.G.A., Otero, X.L., Fernández, E.V., Fernandes, J.O., Cunha, S.C., Guilhermino, L., 2023. Are microplastics contributing to pollution-induced neurotoxicity? A pilot study with wild fish in a real scenario. Heliyon, 9, 1, e13070. https://doi.org/10.1016/j.heliyon.2023.e13070.

Barboza, L.G.A., Vieira, R.L., Branco, V., Figueiredo, N., Carvalho, F., Carvalho, C., Guilhermino L., 2020. Microplastics in wild fish from North East Atlantic Ocean and its potential for causing neurotoxic effects, lipid oxidative damage, and human health risks associated with ingestion exposure. Science of The Total Environment, 717. https://doi.org/10.1016/j.scitotenv.2019.134625.

Bastos, W.R., Dórea, J.G., Bernardi, J.V.E., Manzatto, A.G., Mussy, M.H., Lauthartte, L.C., Lacerda, L.D., Malm, O., 2016. Sex-related mercury bioaccumulation in fish from the Madeira River, Amazon. Environmental Research, 144, 73-80. http://dx.doi.org/10.1016/j.envres.2015.11.001

Bauer, A.L., Ferraz, M., Souza, V.C., Schulz, U.H. 2022. Far from urban areas: plastic uptake in fish populations of subtropical headwater streams. Brazilian Journal of Biology, v. 82, e267886. https://doi.org/10.1590/1519-6984.267886.

Bermúdez-Guzmán, J.M., Sibajá-Cordero, J.A., Villalobos, C., Vargas-Zamora, J.A. 2020. Microplastic ingestion by a herring Opisthonema sp. in the Pacific coast of Costa Rica. Regional Studies in Marine Science, v. 36, 101312. https://doi.org/10.1016/j.rsma.2020.101367.

Bhagat, J., Nishimura, N., Shimada, Y., 2021. Interações toxicológicas de microplásticos/nanoplásticos e contaminantes ambientais: conhecimento atual e perspectivas futuras. Revista de Materiais Perigosos, 405, 123913. https://doi.org/10.1016/j.jhazmat.2020.123913.

Blankson, E.R., Tetteh, P.N., Oppong, P., Gbogbo, F., 2022. Microplastics prevalence in water, sediment and two economically important species of fish in an urban riverine system in Ghana. PLOS ONE, 17, 2, 0263196. https://doi.org/10.1371/journal.pone.0263196.

Blonç, M., Husson, F., Llorca, M., Farré, M., Tort, L., Brandts, I., Teles, M., 2023. Occurrence and tissue-specific accumulation of micro- and nanoplastics in Nile tilapia reared in a recirculating aquaculture system. Environmental Pollution, 336, 122519,: https://doi.org/10.1016/j.hazadv.2023.100381.

Boucher, J., Faure, F., Pompini, O., Plummer, Z., Wieser, O., Alencastro, L.F., 2019. (Micro) plastic fluxes and stocks in Lake Geneva basin. TrAC Trends in Analytical Chemistry, 112, 66-74. https://doi.org/10.1016/j.trac.2018.11.037.

Burger, J., 2007. A framework and methods for incorporating gender-related issues in wildlife risk assessment: Gender-related differences in metal levels and other contaminants as a case study. Environmental Research, 104, 153-162. 10.1016/j.envres.2006.08.00.

Carpenter, E.J., Smith, K.L. Jr. 1972. Plastics on the Sargasso Sea surface. Science, v. 175, n. 4027, p. 1240-1241. https://doi.org/10.1126/science.175.4027.1240.

Collard, F., Gilbert, B., Eppe, G., Roos, L., Compère, P., Das, K., Parmentier, E., 2017. Morphology of the filtration apparatus of three planktivorous fishes and relation with ingested anthropogenic particles. Marine Pollution Bulletin, 116, 182–191, https://doi.org/10.1016/j.marpolbul.2016.12.067.

COMITESINOS. Plano da Bacia Hidrográfica do Rio dos Sinos (Sinos River Basin Plan). 2014. https://www.sema.rs.gov.br/g020-bh-sinos

Corrêa, F., Piedras, S.R.N. 2008. Alimentação de Cyphocharax voga (Hensel, 1869) (Characiformes, Curimatidae) no arroio Corrientes, Pelotas, Rio Grande do Sul, Brasil. Biotemas, Pelotas, v. 21, n. 4, p. 117–122. https://doi.org/10.5007/2175-7925.2008v21n4p117.

Crawford, C.B., Quinn, B., 2017. Microplastic pollutants. Amsterdam: Elsevier, https://www.researchgate.net/publication/313404867_Microplastic_Pollutants.

Dar, M. A.; Palsania, P.; Satya, S.; Dashora, M.; Bhat, O. A.; Parveen, S.; Patidar, S. K.; Kaushik, G. 2025. Microplastic pollution: A global perspective in surface waters, microbial degradation, and corresponding mechanism. Marine Pollution Bulletin, v. 210, p. 117344. https://doi.org/10.1016/j.marpolbul.2024.117344

Deng, Y., Zhang, Y., Lemos, B., Ren, H., 2017. Tissue accumulation of microplastics in mice and its biomarker responses. Scientific Reports, [S.l.], 7, 46687, 1-10. https://doi.org/10.1038/srep46687 (accessed 05 June 2025).

El-Ghazaly, N.A., Hafez, A.M., Wahbi, O.M., Ghanem, S., 2017. Influence of sex on the accumulation and distribution of some trace metals in Sardinella aurita from three sites in Alexandria and the northern coast of Egypt. The Egyptian Journal of Experimental Biology (Zoology), 12, 1, 31–33. https://www.researchgate.net/publication/371043871.

Elsey, D., Jameson, D., Raleigh, B., Cooney, M.J., 2007. Fluorescent measurement of neutral lipids in microalgae. Journal of Microbiological Methods, 68, 3, 639-642. https://doi.org/10.1016/j.mimet.2006.11.008.

Fernandes, A.N., Bertoldi, C., Lara, L.Z., Stival, J., Alves, M.N., Cabrera, P.M., Grassi, M.T., 2022. Microplastics in Latin America ecosystems: a critical review of the current stage and research needs. Journal of the Brazilian Chemical Society, 33, 4, 303-326. https://doi.org/10.21577/0103-5053.20220018.

Ferraz, M., Bauer, A.L., Valiati, L.H., Schulz, U.H., 2020. Microplastic concentrations in raw and drinking water in the Sinos River, Southern Brazil. Water, 12, 11, 1-10. https://www.mdpi.com/2073-4441/12/11/3115.

Gamboa, A.C., Gaida, W., Volpi, G.B., Deitos, T., Machado, A.M.A., Breunig, F.M., Da Rosa, G.M., Flach, K.A., 2025. Microplastics in rivers of South America: an emerging area of research. Sociedade e Natureza, Uberlândia, 37, e74055, https://doi.org/10.14393/SN-v37-2025-74055.

Gewurtz, S.B., Bhavsar, S.P., Fletcher, R. 2011. Influence of fish size and sex on mercury/PCB concentration: importance for fish consumption advisories. Environment International, v. 37, p. 425–434. https://www.sciencedirect.com/science/article/pii/S0160412010002069.

Gomez, B.C., Ejares, F.M.S., Baculpo, P.R., Indig, C.I., Madrona, A.A., Tuyor, R.C., 2023. Ingestion of microplastics by bigeye scad, Selar crumenophthalmus in municipal waters of Malimono, Surigao del Norte, Philippines. International Journal of Biology, 22, 4, 45-54. http://dx.doi.org/10.12692/ijb/22.4.45-54.

Guillante, T., Fonseca, J.S., Costa, P.G., Bianchini, A., Robaldo, R.B., Zebral, Y.D. 2023. Sex-biased response of pollution biomarkers in fish: insights from the killifish Poecilia vivipara. Aquatic Toxicology, v. 261, 106613. https://doi.org/10.1016/j.aquatox.2023.106613.

Guzman, M.K., Andjelković, M., Jovanović, V., Jung, J., Kim, J., Dailey, L.A., Rajković, A., Meulenaer, B., Veličković, T.C., 2022. Comparative profiling and exposure assessment of microplastics in differently sized Manila clams from South Korea by μFTIR and Nile Red staining. Marine Pollution Bulletin, 181, 1-12. https://doi.org/10.1016/j.marpolbul.2022.113846.

Habumugisha, T., Zhang, Z., Fang, C., Yan, C., Zhang, X., 2023. Uptake, bioaccumulation, biodistribution and depuration of polystyrene nanoplastics in zebrafish (Danio rerio). Science of the Total Environment, 893, 164840. https://doi.org/10.1016/j.scitotenv.2023.164840.

Harikrishnam, H., Han, B., Shi, Y., Qian, X., Zhang, K., Yin, S., 2023. Chronic exposure to weathered polyethylene microplastics triggers immune suppression and oxidative stress in freshwater fish Danio albolineatus: sex-specific responses. Aquatic Toxicology, 261, 106619. https://doi.org/10.1016/j.aquatox.2023.106619.

Hendrickson, E., Minor, E.C., Schreiner, K., 2018. Abundance and composition of microplastics in western Lake Superior as determined via microscopy, Pyr-GC/MS, and FTIR. Environmental Science & Technology. 52(4), 1787–1796. https://pubs.acs.org/doi/10.1021/acs.est.7b05829.

Huang, J.S., Koongolla, J.B., Li, H.X., Lin, L., Pan, Y.F., Liu, S., He, W.H., Maharana, D., Xu, X.R., 2020. Microplastic accumulation in fish from Zhanjiang mangrove wetland, South China. Science of the Total Environment, 708, 134839. https://doi.org/10.1016/j.scitotenv.2019.134839.

INSTITUTO OCEANOGRÁFICO DA UNIVERSIDADE DE SÃO PAULO (IO-USP). 2025. Bioacumulação e biomagnificação (Bioaccumulation and biomagnification). https://www.io.usp.br/index.php/oceanos/textos/antartida/31-portugues/publicacoes/series-divulgacao/poluicao/811-bioacumulacao-e-biomagnificacao.html.

Islam, M.S., Islam, A.R.M.T., Ismail, Z., Ibrahim, K.A., AI-Qthanin, R.N., Idris, A.M., 2024. Effects of microplastics and heavy metals on coral reefs: a new window for analytical research. Heliyon, 9, 11, e22692. https://doi.org/10.1016/j.heliyon.2023.e22692.

James, K., Vasant, K., Padua, S., Gopinath, V., Abilash, K.S., Jeyabaskaran, R., Babu, A., John, S., 2020. An assessment of microplastics in the ecosystem and selected commercially important fishes off Kochi, south eastern Arabian Sea, India. Marine Pollution Bulletin, 154, 111027. https://doi.org/10.1016/j.marpolbul.2020.111027.

Karami, A., Golieskardi, A., Choo, C.K., Romano, N., Ho, Y.B., Salamatinia, B., 2017. A high-performance protocol for extraction of microplastics in fish. Science of The Total Environment, 578, 485-494. https://doi.org/10.1016/j.scitotenv.2016.10.213.

Kelly, E.R.M., Trujillo, J.E., Setiawan, A., Pether, S., Burritt, D., Allan, B.J.M., 2024. Investigating metabolic and oxidative stress induced by exposure to biofouled microplastics in Seriola lalandi (yellowtail kingfish). Marine Pollution Bulletin. 203, 116438. https://doi.org/10.1016/j.marpolbul.2024.116438.

Kim, Jun-Hwan, Yu, Young-Bin, Choi, Jae-Ho. 2021. Toxic effects on bioaccumulation, hematological parameters, oxidative stress, immune responses and neurotoxicity in fish exposed to microplastics: a review. Journal of Hazardous Materials, v. 413. https://doi.org/10.1016/j.jhazmat.2021.125423.

Lambert, S., Wagner, M. 2018. Microplastics are contaminants of emerging concern in freshwater environments: an overview. In: WAGNER, Martin, LAMBERT, Scott (org.). Freshwater microplastics: emerging environmental contaminants? Cham: Springer p. 1-23. https://doi.org/10.1007/978-3-319-61615-5_1.

Li, J., Wang, Z., Rotchell, J.M., Shen, X., Li, Q., Zhu, J., 2021. Where are we? Toward an understanding of selective microplastic accumulation in mussels. Environmental Pollution. 286, 117543. https://doi.org/10.1016/j.envpol.2021.117543.

Maes T., Jessop, R., Wellner, N., Haupt, K., Mayes, A.G., 2017. A rapid-screening approach to detect and quantify microplastics based on fluorescent tagging with Nile Red. Scientific Reports, 7, 44501. https://www.nature.com/articles/srep44501.

Mahidev, R.S., Aravind, G.H., Sandeep, K., Arya, S., Santosh, M., Shaji, E., 2024. Microplastics in freshwater lakes: a case study from southern India. Geosystems and Geoenvironment. 3(4), 100306. https://doi.org/10.1016/j.geogeo.2024.100306.

Mancuso, M., Panarello, G., Falco, F., Di Paola, D., Serena, S., Capillo, G., Romeo, T., Presti, G., Gullotta, E., Spanò, N.C.,Bono, G., Salvatore G., Bottari, T., 2022. Investigating the effects of microplastic ingestion in Scyliorhinus canicula from the South of Sicily. Science of the Total Environment, 850, 157875. https://doi.org/10.1016/j.scitotenv.2022.157875.

Masson, N., Castelain, J.G., Dubny, S., Othax, N., Peluso, F., 2021. Biotic integrity index based on fish assemblages in Pampean streams and its application along the Del Azul stream (Buenos Aires Province, Argentina). Acta Limnologica Brasiliensia. 33, 1–16. https://doi.org/10.1590/S2179-975X8220.

Mattsson, K., Hansson, L.A., Linse, S., Malmendal, A., Cederval, T., 2014. Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain. Biophysical Journal, 106, 2 (Supplement 1), 346a. https://doi.org/10.1016/j.bpj.2013.11.3454.

Mattsson, K., Johnson, E.V., Malmendal, A., Linse, S., Hansson, L.A., Cedervall T., 2017. Brain damage and behavioral disorders in fish induced by plastic nanoparticles delivered through the food chain. Scientific Reports, 7, 1, 11452. https://doi.org/10.1038/s41598-017-10813-0.

Montagner, C.C., Dias, M.A., Paiva, E.M., Vidalet, C., 2021. Microplastics: environmental occurrence and analytical challenges. Química Nova. 44(10), 1328–1352. http://dx.doi.org/10.21577/0100-4042.20170791.

Nihart, A.J., Garcia, M.A., Hayek, E.E., Liu, R., Olewine, M., Kingston, J.D., Castillo, E.F., Gullapalli, R.R., Howard, T., Bleske, B., Scott, J., Gonzalez-Estrella, J., Gross, J.M., Spilde, M., Adolphi, M., Gallego, D.F., Jarrell, H.S., Dvorscak, G., Zuluaga-Ruiz, M.E., West, A.B., Campen, M.J., 2025. Bioacumulação de microplásticos em cérebros humanos falecidos. Medicina Natural, 31, 1114–1119. https://www.nature.com/articles/s41591-024-03453-1.

Oliveira, E.A., Baldan, L.T.R., 2022. Ecotoxicologia (Ecotoxicology). São Paulo: Manole. https://palotina.ufpr.br/wp-content/uploads/2022/10/Ecotoxicologia-Oliveira-e-Baldan.pdf

Olson, K.R. (org.), 2014. Manual de toxicologia clínica [recurso eletrônico]. 6. ed. Porto Alegre: AMGH. Revisão técnica da Tabela II 51 por Paulo Luiz de Oliveira. ISBN 978 85 8055 266 9. https://www.meulivro.biz/toxicologia/1499/manual-de-toxicologia-clinica-olson-6-ed-pdf/.

Parker, B., Britton, J.R., Green, I.D., Jackson, M.C., Andreou, D., 2024. Microplastic-stressor responses are rarely synergistic in freshwater fishes: a meta-analysis. Science of the Total Environment, 947, 174566. https://doi.org/10.1016/j.scitotenv.2024.174566.

Polverino, G., Aich, U., Brand, J.A., Bertram, M.G., Martin, J.M., Tan, H., Soman, V.R., Mason, R.T., Wong, B.B.M., 2023. Sex-specific effects of psychoactive pollution on behavioral individuality and plasticity in fish. Behavioral Ecology, 34(6), 969-978. https://doi.org/10.1093/beheco/arad065.

Pompêo, M.L.M., Soares, M.C., Silva, F., Vieira, C.M., 2022. Aspectos da ecotoxicidade em ambientes aquáticos (Aspects of ecotoxicity in aquatic environments). Instituto de Biociências – IB/USP Universidade de São Paulo. https://ecologia.ib.usp.br/portal/ecotoxicidade/index_arquivos/0_all_book_ecotoxicidade.pdf

Rahman, R-R., Baqee, A., Alam, M., Khan, M.W., Muhib, M.I., Kabir, A., 2024. Organ-specific bioaccumulation of microplastics in market fish of Dhaka and size-dependent impacts of PVC microplastics on growth of Anabus testudineus. Environmental Pollution, 361. https://doi.org/10.1016/j.envpol.2024.124807.

Raulin, A.C., Martens, Y.A., Bu, G. 2022. Lipoproteins in the Central Nervous System: From Biology to Pathobiology. Annual Review of Biochemistry, v. 91, p. 731–759. https://doi.org/10.1146/annurev-biochem-032620-104801.

Ribeiro, F., Duarte, A.C., Costa, J.P., 2024. Staining methodologies for microplastics screening. Trends in Analytical Chemistry, 172, 117555. https://doi.org/10.1016/j.trac.2024.117555.

RIO GRANDE DO SUL. Secretaria Estadual do Meio Ambiente. Relatório Técnico 2 – Bacia Hidrográfica do Baixo Jacuí (RT2). Porto Alegre: SEMA-RS, 2023. https://sema.rs.gov.br/g070-bh-baixo-jacui?utm_source=chatgpt.com.

Rocha, M.A., Ribeiro, E.L.A., Mizubuti, I.Y., Silva, L.D.F., Borosky, J.C., Rubin, K.C.P., 2005. Utilização dos fatores de condição alométricos e de Fulton para comparar a carpa (Cyprinus carpio) considerando sexos e idades. Revista Brasileira de Zootecnia, 26, 3, 429-436. https://doi.org/10.5433/1679-0359.2005v26n3p429.

Rossatto, A., Arlindo, M.Z.F., Morais, M.S., Souza, T.D., Ogrodowski, C.S., 2024. Microplastics in aquatic systems: a review of occurrence, monitoring, and potential environmental risks. Environmental Advances. 13, 1–19. https://doi.org/10.1016/j.envadv.2023.100396

Salla, R.F., Oliveira, F.N., Jacintho, J.C., Cirqueira, F., Tsukada, E., Vieira, L.G., Rocha, T.L., 2024. Microplastics and TiO₂ nanoparticles mixture as an emerging threat to amphibians: a case study on bullfrog embryos. Environmental Pollution, 346, 123624. https://doi.org/10.1016/j.envpol.2024.123624.

Sbrana, A., Valente, T., Scacco, U., Bianchi, J., Silvestri, C., Palazzo, L., Lucia, G.A., Valerani, C., Ardizzone, G., Matiddi, M., 2020. Spatial variability and influence of biological parameters on microplastic ingestion by Boops boops (L.) along the Italian coasts (Western Mediterranean Sea). Environmental Pollution, 263, 114429. https://doi.org/10.1016/j.envpol.2020.114429.

Schifino, L.C., Fialho, C.B., Verani, J.R. 1998. Reproductive aspects of Cyphocharax voga (Hensel) from Custódias Lagoon, Rio Grande do Sul, Brazil (Characiformes, Curimatidae). Rev. Bras. Zool. 15 (3). https://doi.org/10.1590/S0101-81751998000300019.

Shan, S., Zhang, Y., Zhao, H., Zeng, T., Zhao, T., 2022. Polystyrene nanoplastics penetrate the blood–brain barrier and induce microglial activation in the mouse brain. Chemosphere. 298, 134261. https://doi.org/10.1016/j.chemosphere.2022.134261

Shi, Y., Chen, W., Yang, S., Fan, Y., Lu, L., 2024. Freshwater microplastic governance and sustainable development: pollution status, interactions, policies, and prospective studies. Desalination and Water Treatment. 320, 1–13. https://doi.org/10.1016/j.dwt.2024.100704

Silva, D.C., Vieira, H.A.G., Rolim, V.S., Silva, W.F., Sousa, M.G., Paulino, M.G., Mariano, W.S., 2021. Contaminantes ambientais: efeitos dos microplásticos em organismos aquáticos e terrestres. Research, Society and Development. 10(7), e54310716761. https://doi.org/10.33448/rsd-v10i7.16761

Silveira, D., Gomes, L.P., Caetano, M.O., Lima, K.C., Valiati, V.H., Schulz, U.H., 2024. Microplastic contamination in the liver of iliophagous fish in an urbanized river of subtropical climate in southern South America. Acta Biologica Brasiliensia, 7, 2, 83-102. https://doi.org/10.18554/acbiobras.v7i2.7772.

Sultana, S., Anisuzzaman, M., Hossain, K., Rana, S., Paray, B.A., Arai, T., Yu, J., Hossain, B., 2024. Ecological risk assessment of microplastics and mesoplastics in six common fish species from the Bay of Bengal coast. Marine Pollution Bulletin. 204, 1–13. https://doi.org/10.1016/j.marpolbul.2024.116544

Wang, X., Jian, S., Zhang, S., Wu, D., Wang, J., Gao, M., Sheng, J., Hong, Y., 2022. Enrichment of polystyrene microplastics induces histological damage, oxidative stress, Keap1-Nrf2 signaling pathway-related gene expression in loach juveniles (Paramisgurnus dabryanus). Ecotoxicology and Environmental Safety, 237, 1-11. https://doi.org/10.1016/j.ecoenv.2022.113540.

Yee, M.S.L., Hi, L.W., Looi, C.K., Lim, W.M., Wong, S.F., Kok, Y.Y., Tan, B.K., Wong, C.Y., Leong, C.O., 2021. Impact of microplastics and nanoplastics on human health. Nanomaterials, Basel, 11, 2, 1-22. https://www.mdpi.com/2079-4991/11/2/496

Yin, J., Ju, Y., Qian, H., Wang, J., Miao, X., Zhu, Y., Zhou, L., Ye, L., 2022. Nanoplastics and microplastics may be damaging our livers. Toxics, 10, 10, 1-32. https://doi.org/10.3390/toxics10100586.

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2026-05-05

Cómo citar

de Silveira, D. C., de Lima, K. C., Schulz, U. H., Kieling, A. G., Caetano, M. O., & Gomes, L. P. (2026). EVALUACIÓN DE MICROPLÁSTICOS EN HÍGADO, RIÑÓN, CEREBRO Y MÚSCULO DEL PEZ CYPHOCHARAX VOGA. Revista De Geopolítica, 17(5), e2323. https://doi.org/10.56238/revgeov17n5-005