COMPACT CANINE THYROID CARCINOMA: A CASE REPORT IN A SRD DOG FROM ANÁPOLIS-GO
DOI:
https://doi.org/10.56238/revgeov16n4-084Keywords:
Thyroid Carcinoma, Veterinary Oncology, Dogs, Histopathology, TreatmentAbstract
This study describes a clinical case of compact thyroid carcinoma in an elderly mixed-breed female dog, attended in Anápolis, Goiás, Brazil. The diagnosis was established through histopathological analysis, which revealed a malignant neoplasm with aggressive behavior and invasive potential. Literature review showed that thyroid carcinomas in dogs are relatively uncommon but present high clinical relevance due to their reserved prognosis and the demand for specific therapeutic approaches. The main treatment modalities were discussed, including surgery, radioiodine therapy, and targeted therapies such as toceranib, which have demonstrated clinical benefits in advanced cases. It is concluded that a multidisciplinary approach, early diagnosis, and appropriate therapeutic choice are essential to prolong survival and improve patients’ quality of life. This report contributes to the regional scientific record and to the advancement of knowledge in veterinary oncology.
Downloads
References
BIRCHARD, S. J.; SHERDING, R. G. Manual Saunders de clínica de pequenos animais. 3. ed. São Paulo: Roca, 2016. Disponível em: https://books.google.com.br/books/about/Manual_Saunders_Cl%C3%ADnica_de_Pequenos_Ani.html?id=yLEngvzqpisC&redir_esc=y Acesso em: 01 Set. 2025.
BRODEY, R. S.; KELLY, D. F. Thyroid neoplasms in the dog. A clinicopathologic study of fifty-seven cases. Cancer, v. 22, n. 2, p. 406-416, 1968. Disponível em: https://pubmed.ncbi.nlm.nih.gov/5660204. DOI: 10.1002/1097-0142(196808)22:2<406::aid-cncr2820220219>3.0.co;2-b. Acesso em: 10 set. 2025.
CAPEN, C. C. Tumors of the endocrine glands. In: MEUTEN, D. J. (ed.). Tumors in Domestic Animals. 4. ed. Iowa: Iowa State Press, 2002. Disponível em: https://pmc.ncbi.nlm.nih.gov/articles/PMC340250/ Acesso em: 30 Agosto. 2025
CARVALHO, G. L. C. Frequência de neoplasias endócrinas em cães e perfil da população afetada em uma rotina de atendimento em endocrinologia. 2012. 24 f. TCC (Graduação em Medicina Veterinária) – Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, 2012. Disponível em: https://lume.ufrgs.br/bitstream/handle/10183/69790/000873774.pdf?sequence=1. Acesso em: 10 set. 2025.
DAGLI, M. L. Z.. Tratado de medicina interna de cães e gatos. Disponível em: https://mktgen.com.br/ROC/Sumario/9788527726436_SUM.pdf Acesso em: 03 Set. 2025.
ENACHE, A. et al. Thyroidectomy in dogs with thyroid tumors: Survival analysis in 144 cases (1994–2018). Journal of Veterinary Internal Medicine, v. 37, n. 2, p. 635-647, 2023. Disponível em: https://onlinelibrary.wiley.com/doi/full/10.1111/jvim.16644. Acesso em: 08 set. 2025.
FELDMAN, E. C.; NELSON, R. W. Canine and Feline Endocrinology. 4. ed. St. Louis: Elsevier, 2015. Disponível em: https://pmc.ncbi.nlm.nih.gov/articles/PMC5508930/ Acesso em: 05 Set. 2025.
FIGHERA, R. A. et al. Neoplasmas da tireoide em cães: 26 casos. Pesquisa Veterinária Brasileira, v. 37, n. 12, p. 1460-1466, 2017. Disponível em: http://dx.doi.org/10.1590/s0100-736x2017001200016. Acesso em: 05 set. 2025.
FREDERICK, A. N. et al. Outcomes for dogs with functional thyroid tumors treated by surgical excision alone. Journal of the American Veterinary Medical Association, v. 256, n. 4, p. 444-448, 2020. Disponível em: https://doi.org/10.2460/javma.256.4.444. Acesso em: 05 set. 2025.
GALLI, G. M. et al. Exposição ambiental e risco de neoplasias em cães e gatos: revisão. Acta Scientiae Veterinariae, v. 49, n. 1, p. 1-12, 2021. Disponível em: https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/issue/view/4209 Acesso em: 25 Agosto, 2025.
GIANNASI, N. P. Prevenção e diagnóstico precoce de tumores em pequenos animais. Revista Clínica Veterinária, v. 26, n. 153, p. 36-43, 2021.
JUBB, K. V. F.; KENNEDY, P. C.; PALMER, N. Pathology of Domestic Animals. 6. ed. Philadelphia: Elsevier, 2016.
MEUTEN, D. J. Tumors in Domestic Animals. 5. ed. Iowa: Wiley Blackwell, 2016.
MOONEY, C. P. Canine thyroid tumors. Clinical Techniques in Small Animal Practice, v. 20, n. 1, p. 45-52, 2005. Disponível em: https://pubmed.ncbi.nlm.nih.gov/15907038. Acesso em: 07 set. 2025.
OWEN, L. N. TNM classification of tumours in domestic animals. Geneva: World Health Organization, 1980. Disponível em: https://apps.who.int/iris/handle/10665/68618. Acesso em: 02 set. 2025.
SHEPPARD-OLIVARES, A. et al. Clinical outcome and prognostic factors for dogs with thyroid carcinoma treated with toceranib phosphate: 42 cases (2009–2018). Veterinary and Comparative Oncology, v. 18, n. 3, p. 331-341, 2020. Disponível em: https://onlinelibrary.wiley.com/doi/10.1111/vco.12571. Acesso em: 09 set. 2025.
WITHROW, S. J.; VAIL, D. M. Withrow and MacEwen’s Small. Animal Clinical Oncology. 6. ed. St. Louis: Elsevier, 2020. Disponível em: https://www.academia.edu/42258979/Small_Animal_Clinical_Oncology Acesso em: 19 Agosto, 2025.
WUCHERER, C.; WILKE, V. Thyroid carcinoma in dogs: a retrospective study of 50 cases. Tierärztliche Praxis Kleintiere, v. 38, p. 333-340, 2010. Disponível em: https://pubmed.ncbi.nlm.nih.gov/20610697/ Acesso em: 27 Agosto, 2025.
